Dynole 34-2

• Supplier: Tocris Bioscience
• Catalog: 2897
• Prices: $189.00, $765.00
• Sizes: 10 mg, 50 mg
• Function Type: Inhibitor
• Cas Number: 1128165-88-7
• Chemical Name: 2-Cyano-3-[1-[3-(dimethylamino)propyl]-1H-indol-3-yl]-N-octyl-2-propenamide
• Formula: C25H36N4O
• Molecular Weight: 408.58
• Purity: >99 %
• Description: Dynamin I inhibitor (IC 50 = 1.3 μ M). Inhibits receptor-mediated endocytosis (RME) (IC 50 = 5.0 μ M).

Product References

Inhibition of dynamin mediated endocytosis by the dynoles--synthesis and - Inhibition of dynamin mediated endocytosis by the dynoles--synthesis and

Hill TA, Gordon CP, McGeachie AB, Venn-Brown B, Odell LR, Chau N, Quan A, Mariana A, Sakoff JA, Chircop M, Robinson PJ, McCluskey A. J Med Chem. 2009 Jun 25;52(12):3762-73.

Iminochromene inhibitors of dynamins I and II GTPase activity and endocytosis. - Iminochromene inhibitors of dynamins I and II GTPase activity and endocytosis.

Hill TA, Mariana A, Gordon CP, Odell LR, Robertson MJ, McGeachie AB, Chau N, Daniel JA, Gorgani NN, Robinson PJ, McCluskey A. J Med Chem. 2010 May 27;53(10):4094-102.