EBPC

• Supplier: Tocris Bioscience
• Catalog: 1041
• Prices: $129.00, $535.00
• Sizes: 10 mg, 50 mg
• Function Type: Inhibitor
• Cas Number: 4450-98-0
• Chemical Name: Ethyl1-benzyl-3-hydroxy-2(5H)-oxopyrrole-4-carboxylate
• Formula: C14H15NO4
• Molecular Weight: 261.28
• Purity: >99 %
• Description: Potent aldose reductase inhibitor. Improves the cytotoxicity of anticancer reagents such as cisplatin (Cat.No. 2251) and doxorubicin (Cat.No. 2252) in HeLa cervical carcinoma cells through an increase in ERK activity.

Product References

A highly specific aldose reductase inhibitor, ethyl - A highly specific aldose reductase inhibitor, ethyl

Mylari BL, Beyer TA, Siegel TW. J Med Chem. 1991 Mar;34(3):1011-8.

Inhibition of aldose reductase enhances HeLa cell sensitivity to chemotherapeutic - Inhibition of aldose reductase enhances HeLa cell sensitivity to chemotherapeutic

Lee EK, Regenold WT, Shapiro P. Anticancer Drugs. 2002 Sep;13(8):859-68.