Ebselen

Name Ebselen
Supplier Tocris Bioscience
Catalog 0518
Prices $75.00, $315.00
Sizes 10 mg, 50 mg
Cas Number 60940-34-3
Chemical Name 2-Phenyl-1,2-benzisoselenazol-3(2H)-one
Formula C13H9NOSe
Molecular Weight 274.18
Purity >98 %
Description Glutathione peroxidase mimic; peroxynitrite scavenger. Inhibits lipoxygenase, cyclooxygenase, nitric oxide synthase, protein kinase C and H + /K + -ATPase activity. Inhibits the hepatic carcinogenic effects of aflatoxin B 1 . Antioxidant and anti-inflammatory.
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Product References

Molecular actions of ebselen--an antiinflammatory antioxidant. - Molecular actions of ebselen--an antiinflammatory antioxidant.

Schewe T. Gen Pharmacol. 1995 Oct;26(6):1153-69.

Inhibition of ebselen on aflatoxin B(1)-induced hepatocarcinogenesis in Fischer - Inhibition of ebselen on aflatoxin B(1)-induced hepatocarcinogenesis in Fischer

Yang CF, Liu J, Wasser S, Shen HM, Tan CE, Ong CN. Carcinogenesis. 2000 Dec;21(12):2237-43.

Kinetic studies of the radical-scavenging activity of ebselen, a seleno-organic - Kinetic studies of the radical-scavenging activity of ebselen, a seleno-organic

Fujisawa S, Kadoma Y. Anticancer Res. 2005 Nov-Dec;25(6B):3989-94.