Edaglitazone

• Supplier: Tocris Bioscience
• Catalog: 3202
• Prices: $139.00, $585.00
• Sizes: 10 mg, 50 mg
• Function Type: Agonist
• Cas Number: 213411-83-7
• Chemical Name: 5-[[4-[2-(5-Methyl-2-phenyl-4-oxazolyl)ethoxy]benzo[b]thien-7-yl]methyl]-2,4-thiazolidinedione
• Formula: C24H20N2O4S2
• Molecular Weight: 464.56
• Purity: >98 %
• Description: Potent and selective PPAR γ agonist (EC 50 values are 35.6 and 1053 nM for PPAR γ and PPAR α cofactor recruitment respectively. Enhances insulin sensitivity in obese, but not lean, rats. Antidiabetic and orally bioavailable.

Product References

Chronic and acute effects of thiazolidinediones BM13.1258 and BM15.2054 on rat - Chronic and acute effects of thiazolidinediones BM13.1258 and BM15.2054 on rat

Furnsinn C, Brunmair B, Meyer M, Neschen S, Furtmuller R, Roden M, Kuhnle HF, Nowotny P, Schneider B, Waldhausl W. Br J Pharmacol. 1999 Nov;128(6):1141-8.

Comparative molecular profiling of the PPARalpha/gamma activator aleglitazar: - Comparative molecular profiling of the PPARalpha/gamma activator aleglitazar:

Dietz M, Mohr P, Kuhn B, Maerki HP, Hartman P, Ruf A, Benz J, Grether U, Wright MB. ChemMedChem. 2012 Jun;7(6):1101-11.