Ellipticine

• Supplier: Tocris Bioscience
• Catalog: 3058
• Prices: $105.00
• Sizes: 10 mg
• Cas Number: 519-23-3
• Chemical Name: 5,11-Dimethyl-6H-pyrido[4,3-b]carbazole
• Formula: C17H14N2
• Molecular Weight: 246.31
• Purity: >97 %
• Description: Naturally occurring plant alkaloid with antitumor activity. DNA intercalating agent; blocks DNA topoisomerase II activity. Prevents p53 phosphorylation in lung cancer cells.

Product References

Intercalative antitumor drugs interfere with the breakage-reunion reaction of - Intercalative antitumor drugs interfere with the breakage-reunion reaction of

Tewey KM, Chen GL, Nelson EM, Liu LF. J Biol Chem. 1984 Jul 25;259(14):9182-7.

Inhibition of p53 protein phosphorylation by 9-hydroxyellipticine: a possible - Inhibition of p53 protein phosphorylation by 9-hydroxyellipticine: a possible

Ohashi M, Sugikawa E, Nakanishi N. Jpn J Cancer Res. 1995 Sep;86(9):819-27.