Eltoprazine hydrochloride

• Supplier: Tocris Bioscience
• Catalog: 3357
• Prices: $129.00
• Sizes: 10 mg
• Function Type: Agonist
• Cas Number: 98206-09-8
• Chemical Name: 1-(2,3-Dihydro-1,4-benzodioxin-5-yl)-piperazinehydrochloride
• Formula: C12H16N2O2.HCl
• Molecular Weight: 256.73
• Purity: >98 %
• Description: 5-HT 1 and 5-HT 2C receptor partial agonist (K i values are 40, 52 and 81 nM for 5-HT 1A , 5-HT 1B and 5-HT 2C receptors respectively). Reduces 5-HIAA levels in the striatum and exhibits antiaggressive behavior in vivo .

Product References

Brain 5-HT and inhibition of aggressive behavior in animals: 5-HIAA and receptor - Brain 5-HT and inhibition of aggressive behavior in animals: 5-HIAA and receptor

Miczek KA, Mos J, Olivier B. Psychopharmacol Bull. 1989;25(3):399-403.

Neurochemical profile of eltoprazine. - Neurochemical profile of eltoprazine.

Schipper J, Tulp MT, Sijbesma H. Drug Metabol Drug Interact. 1990;8(1-2):85-114.

Discriminative stimulus properties of eltoprazine. - Discriminative stimulus properties of eltoprazine.

Gommans J, Hijzen TH, Maes RA, Olivier B. Life Sci. 1997;61(1):11-9.