EMD 66684

Name EMD 66684
Supplier Tocris Bioscience
Catalog 2382
Prices $199.00, $825.00
Sizes 10 mg, 50 mg
Function Type Antagonist
Cas Number 1216884-39-7
Chemical Name 2-Butyl-3,4-dihydro-N,N-dimethyl-4-oxo-3-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl-4-yl]methyl]-5H-imidazo[4,5-c]pyridine-5-acetamidehydrochloride
Formula C28H30N8O2.HCl
Molecular Weight 547.05
Purity >98 %
Description Highly potent and very selective non-peptide angiotensin AT 1 receptor antagonist (IC 50 values are 0.7 and > 10000 nM for AT 1 and AT 2 receptors respectively). Potently inhibits angiotensin II-induced contractions in isolated rabbit aorta (IC 50 = 0.2 nM) and reduces blood pressure in hypertensive rats.
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