Name | EMD 66684 |
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Supplier | Tocris Bioscience |
Catalog | 2382 |
Prices | $199.00, $825.00 |
Sizes | 10 mg, 50 mg |
Function Type | Antagonist |
Cas Number | 1216884-39-7 |
Chemical Name | 2-Butyl-3,4-dihydro-N,N-dimethyl-4-oxo-3-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl-4-yl]methyl]-5H-imidazo[4,5-c]pyridine-5-acetamidehydrochloride |
Formula | C28H30N8O2.HCl |
Molecular Weight | 547.05 |
Purity | >98 % |
Description | Highly potent and very selective non-peptide angiotensin AT 1 receptor antagonist (IC 50 values are 0.7 and > 10000 nM for AT 1 and AT 2 receptors respectively). Potently inhibits angiotensin II-induced contractions in isolated rabbit aorta (IC 50 = 0.2 nM) and reduces blood pressure in hypertensive rats. |
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