β -Estradiol

Name β -Estradiol
Supplier Tocris Bioscience
Catalog 2823
Prices $75.00
Sizes 100 mg
Function Type Agonist
Cas Number 50-28-2
Chemical Name (17β)-Estra-1,3,5(10)-triene-3,17-diol
Formula C18H24O2
Molecular Weight 272.38
Purity >99 %
Description Endogenous estrogen receptor (ER) agonist (K i values are 0.12 and 0.13 nM for ER α and ER β respectively). Also high affinity ligand at membrane estrogen GPR30 receptors. α- Estradiol (Cat. No. 2823) also available.
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Product References

Comparison of the ligand binding specificity and transcript tissue distribution - Comparison of the ligand binding specificity and transcript tissue distribution

Kuiper GG, Carlsson B, Grandien K, Enmark E, Haggblad J, Nilsson S, Gustafsson JA. Endocrinology. 1997 Mar;138(3):863-70.

Identity of an estrogen membrane receptor coupled to a G protein in human breast - Identity of an estrogen membrane receptor coupled to a G protein in human breast

Thomas P, Pang Y, Filardo EJ, Dong J. Endocrinology. 2005 Feb;146(2):624-32. Epub 2004 Nov 11.