( R )-(+)-Etomoxir sodium salt

Name ( R )-(+)-Etomoxir sodium salt
Supplier Tocris Bioscience
Catalog 1471
Prices $169.00, $705.00
Sizes 10 mg, 50 mg
Function Type Inhibitor
Cas Number 828934-41-4
Chemical Name (R)-(+)-2-[6-(4-Chlorophenoxy)hexyl]-oxirane-2-carboxylicacidsodiumsalt
Formula C15H18ClNaO4
Molecular Weight 320.74
Purity >98 %
Description Inhibitor of carnitine palmitoyltransferase I (CPT1); inhibits β -oxidation in mitochondria. Shown to inhibit cardiolipin biosynthesis from exogenous fatty acid in H9c2 cells.
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Product References

Stereospecificity of the inhibition by etomoxir of fatty acid and cholesterol - Stereospecificity of the inhibition by etomoxir of fatty acid and cholesterol

Agius L, Meredith EJ, Sherratt HS. Biochem Pharmacol. 1991 Oct 9;42(9):1717-20.

Modification of subcellular organelles in pressure-overloaded heart by etomoxir, - Modification of subcellular organelles in pressure-overloaded heart by etomoxir,

Rupp H, Elimban V, Dhalla NS. FASEB J. 1992 Mar;6(6):2349-53.

Etomoxir mediates differential metabolic channeling of fatty acid and glycerol - Etomoxir mediates differential metabolic channeling of fatty acid and glycerol

Xu FY, Taylor WA, Hurd JA, Hatch GM. J Lipid Res. 2003 Feb;44(2):415-23. Epub 2002 Nov 4.