Etoposide

• Supplier: Tocris Bioscience
• Catalog: 4539
• Prices: $129.00
• Sizes: 100 mg
• Function Type: Inhibitor
• Cas Number: 33419-42-0
• Chemical Name: [5R-[5α,5aβ,8aα,9β(R*)]]-9-[(4,6-Ο-Ethylidene-β-D-glucopyranosyl)oxy]-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6-(5aH)-one
• Formula: C29H32O13
• Molecular Weight: 588.56
• Purity: >99 %
• Description: Topoisomerase II inhibitor (IC 50 = 59.2 μ M).

Product References

Antitumor agents. 3. Synthesis and biological activity of 4 beta-alkyl - Antitumor agents. 3. Synthesis and biological activity of 4 beta-alkyl

Terada T, Fujimoto K, Nomura M, Yamashita J, Wierzba K, Yamazaki R, Shibata J, Sugimoto Y, Yamada Y, Kobunai T, et al.. J Med Chem. 1993 Jun 11;36(12):1689-99.

Topoisomerase II.etoposide interactions direct the formation of drug-induced - Topoisomerase II.etoposide interactions direct the formation of drug-induced

Burden DA, Kingma PS, Froelich-Ammon SJ, Bjornsti MA, Patchan MW, Thompson RB, Osheroff N. J Biol Chem. 1996 Nov 15;271(46):29238-44.

Etoposide: four decades of development of a topoisomerase II inhibitor. - Etoposide: four decades of development of a topoisomerase II inhibitor.

Hande KR. Eur J Cancer. 1998 Sep;34(10):1514-21.