Evans Blue tetrasodium salt

• Supplier: Tocris Bioscience
• Catalog: 5183
• Prices: $69.00
• Sizes: 1 g
• Function Type: Inhibitor
• Cas Number: 314-13-6
• Chemical Name: 6,6-[(3,3'-Dimethyl[1,1'-biphenyl]-4,4'-diyl)bis(azo)bis[4-amino-5-hydroxy-1,3-naphthalenedisulphonicacid]tetrasodiumsalt
• Formula: C34H24N6Na4O14S4
• Molecular Weight: 960.82
• Purity: >95 %
• Description: Potent inhibitor of L-glutamate uptake into synaptic vesicles. Also inhibits AMPA and kainate receptor-mediated currents (IC 50 values are 220 and 150 nM respectively). P2X-selective purinoceptor antagonist.

Product References

Uptake of L-glutamate into rat brain synaptic vesicles: effect of inhibitors that - Uptake of L-glutamate into rat brain synaptic vesicles: effect of inhibitors that

Roseth S, Fykse EM, Fonnum F. J Neurochem. 1995 Jul;65(1):96-103.

Evans blue antagonizes both alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate - Evans blue antagonizes both alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate

Price CJ, Raymond LA. Mol Pharmacol. 1996 Dec;50(6):1665-71.

P2-purinoceptor antagonists: II. Blockade of P2-purinoceptor subtypes and - P2-purinoceptor antagonists: II. Blockade of P2-purinoceptor subtypes and

Wittenburg H, Bultmann R, Pause B, Ganter C, Kurz G, Starke K. Naunyn Schmiedebergs Arch Pharmacol. 1996 Oct;354(4):491-7.

Differential modulation of AMPA receptor mediated currents by evans blue in - Differential modulation of AMPA receptor mediated currents by evans blue in

Schurmann B, Wu X, Dietzel ID, Lessmann V. Br J Pharmacol. 1997 May;121(2):237-47.