| Name | Fatostatin A |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 0541 |
| Prices | $109.00, $459.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Inhibitor |
| Cas Number | 298197-04-3 |
| Chemical Name | 4-[4-(4-Methylphenyl)-2-thiazolyl]-2-propylpyridinehydrobromide |
| Formula | C18H18N2S.HBr |
| Molecular Weight | 375.33 |
| Purity | >97 % |
| Description | Inhibitor of sterol regulatory element binding protein (SREBP); impairs the activation of SREBP-1 and SREBP-2. Exhibits antiproliferative effects in DU 145 cells independently of IGF-1 signaling (IC 50 = 0.1 μ M); reverses hyperglycemia in diabetic ( ob/ob ) mice. Cell permeable. |
| Supplier Page | Shop |
Choi Y, Kawazoe Y, Murakami K, Misawa H, Uesugi M. J Biol Chem. 2003 Feb 28;278(9):7320-4. Epub 2002 Dec 19.
Kamisuki S, Mao Q, Abu-Elheiga L, Gu Z, Kugimiya A, Kwon Y, Shinohara T, Kawazoe Y, Sato S, Asakura K, Choo HY, Sakai J, Wakil SJ, Uesugi M. Chem Biol. 2009 Aug 28;16(8):882-92.