( Z )-FeCP-oxindole

Name ( Z )-FeCP-oxindole
Supplier Tocris Bioscience
Catalog 3882
Prices $235.00
Sizes 10 mg
Function Type Inhibitor
Cas Number 1137967-28-2
Chemical Name (Z)-3-Ferrocenylmethylidene-1,3-dihydro-2H-indol-2-one
Formula C19H15FeNO
Molecular Weight 329.17
Description Selective inhibitor of human vascular endothelial cell growth factor receptor 2 (VEGFR-2) (IC 50 = 220 nM). Displays anticancer activity (IC 50 < 1 μ M against B16 murine melanoma lines). Does not significantly inhibit VEGFR1 or PDGFRa or b at a concentration of 10 μ M. Geometric isomer of ( E )-FeCP-oxindole (Cat. No. 3882).
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