Fenoldopam hydrochloride

• Supplier: Tocris Bioscience
• Catalog: 4113
• Prices: $175.00, $709.00
• Sizes: 10 mg, 50 mg
• Function Type: Agonist
• Cas Number: 181217-39-0
• Chemical Name: 6-Chloro-2,3,4,5-tetrahydro-1-(4-hydroxyphenyl)-1H-3-benzazepine-7,8-diolhydrochloride
• Formula: C16H16ClNO3.HCl
• Molecular Weight: 342.22
• Purity: >98 %
• Description: Selective D 1 -like dopamine receptor partial agonist (EC 50 = 57 nM). Vasodilator in vivo and does not readily cross the blood-brain barrier. Also α 2 -adrenoceptor antagonist in vitro (K i = 15 - 25 nM).

Product References

Characterization of the peripheral and central effects of SK&F 82526, a novel - Characterization of the peripheral and central effects of SK&F 82526, a novel

Hahn RA, Wardell JR Jr, Sarau HM, Ridley PT. J Pharmacol Exp Ther. 1982 Nov;223(2):305-13.

Interactions of novel dopaminergic ligands with D-1 and D-2 dopamine receptors. - Interactions of novel dopaminergic ligands with D-1 and D-2 dopamine receptors.

Sibley DR, Leff SE, Creese I. Life Sci. 1982 Aug 16;31(7):637-45.

The pharmacology of fenoldopam. - The pharmacology of fenoldopam.

Nichols AJ, Ruffolo RR Jr, Brooks DP. Am J Hypertens. 1990 Jun;3(6 Pt 2):116S-119S.