FG 7142

Name FG 7142
Supplier Tocris Bioscience
Catalog 3878
Prices $159.00
Sizes 100 mg
Function Type Agonist
Cas Number 78538-74-6
Chemical Name N-Methyl-β-carboline-3-carboxamide
Formula C13H11N3O
Molecular Weight 225.25
Purity >99 %
Description Inverse agonist and anxiogenic agent. Increases tyrosine hydroxylation and causes upregulation of β -adrenoceptors in mouse cerebral cortex.
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Product References

A single dose of FG 7142 causes long-term increases in mouse cortical - A single dose of FG 7142 causes long-term increases in mouse cortical

Stanford SC, Little HJ, Nutt DJ, Taylor SC. Eur J Pharmacol. 1987 Feb 24;134(3):313-9.

Evidence for an excitatory action of the benzodiazepine receptor inverse agonist - Evidence for an excitatory action of the benzodiazepine receptor inverse agonist

Donnerer J. Naunyn Schmiedebergs Arch Pharmacol. 1989 Sep;340(3):352-4.

The anxiogenic beta-carboline FG-7142 increases in vivo and in vitro tyrosine - The anxiogenic beta-carboline FG-7142 increases in vivo and in vitro tyrosine

Knorr AM, Deutch AY, Roth RH. Brain Res. 1989 Aug 28;495(2):355-61.

Behavioral studies with the beta-carboline FG 7142 combined with related drugs in - Behavioral studies with the beta-carboline FG 7142 combined with related drugs in

Wettstein JG. Eur J Pharmacol. 1989 Apr 25;163(2-3):219-25.