Filipin III

• Supplier: Tocris Bioscience
• Catalog: 4002
• Prices: $175.00
• Sizes: 1 mg
• Cas Number: 480-49-9
• Chemical Name: (3R,4S,6S,8S,10R,12R,14R,16S,17E,19E,21E,23E,25E,27S,28R)-4,6,8,10,12,14,16,27-Octahydroxy-3-[(1R)-1-hydroxyhexyl]-17,28-dimethyloxacyclooctacosa-17,19,21,23,25-pentaen-2-one
• Formula: C35H58O11
• Molecular Weight: 654.83
• Purity: >98 %
• Description: Polyene antibiotic. Binds sterols in fungal membranes. Also inhibits formation of the pathological form of prion protein (PrP-res) from the normal membrane-bound (PrP-sen) form.

Product References

Four-amino acid segment in steroid 5 alpha-reductase 1 confers sensitivity to - Four-amino acid segment in steroid 5 alpha-reductase 1 confers sensitivity to

Thigpen AE, Russell DW. J Biol Chem. 1992 Apr 25;267(12):8577-83.

Comparison of the pharmacological effects of a novel selective androgen receptor - Comparison of the pharmacological effects of a novel selective androgen receptor

Gao W, Kearbey JD, Nair VA, Chung K, Parlow AF, Miller DD, Dalton JT. Endocrinology. 2004 Dec;145(12):5420-8. Epub 2004 Aug 12.

Studies on neurosteroids XXV. Influence of a 5alpha-reductase inhibitor, - Studies on neurosteroids XXV. Influence of a 5alpha-reductase inhibitor,

Mukai Y, Higashi T, Nagura Y, Shimada K. Biol Pharm Bull. 2008 Sep;31(9):1646-50.