FIT

Name FIT
Supplier Tocris Bioscience
Catalog 5016
Prices $189.00, $765.00
Sizes 10 mg, 50 mg
Function Type Agonist
Cas Number 85951-63-9
Chemical Name N-[1-[2-(4-Isothiocyanatophenyl)ethyl]-4-piperidinyl]-N-phenylpropanamide
Formula C23H27N3OS
Molecular Weight 393.55
Purity >99 %
Description Selective and irreversible δ -opioid agonist (EC 50 = 8 nM); acts by alkylating the receptor.
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Product References

Irreversible ligands with high selectivity toward delta and mu opiate receptors. - Irreversible ligands with high selectivity toward delta and mu opiate receptors.

Rice KC, Jacobson AE, Burke TR Jr, Bajwa BS, Streaty RA, Klee WA. Science. 1983 Apr 15;220(4594):314-6.

Evidence that the delta-selective alkylating agent, fit, alters the - Evidence that the delta-selective alkylating agent, fit, alters the

Rothman RB, Danks JA, Herkenham M, Jacobson AE, Burke TR Jr, Rice KC. Neuropeptides. 1985 Jun;6(3):227-37.

Mu-, delta- and kappa-opioid receptor-mediated inhibition of neurotransmitter - Mu-, delta- and kappa-opioid receptor-mediated inhibition of neurotransmitter

Schoffelmeer AN, Rice KC, Jacobson AE, Van Gelderen JG, Hogenboom F, Heijna MH, Mulder AH. Eur J Pharmacol. 1988 Sep 13;154(2):169-78.