Flufenamic acid

• Supplier: Tocris Bioscience
• Catalog: 3495
• Prices: $59.00
• Sizes: 50 mg
• Cas Number: 530-78-9
• Chemical Name: 2-[[3-(Trifluoromethyl)phenyl]amino]benzoicacid
• Formula: C14H10F3NO2
• Molecular Weight: 281.23
• Purity: >99 %
• Description: Nonsteroidal anti-inflammatory drug (NSAID). Inhibits calcium-activated chloride channels (CaCCs). Also increases currents through TRPC6 channels and inhibits currents through TRPC3 and TRPC7 channels.

Product References

Niflumic and flufenamic acids are potent reversible blockers of Ca2(+)-activated - Niflumic and flufenamic acids are potent reversible blockers of Ca2(+)-activated

White MM, Aylwin M. Mol Pharmacol. 1990 May;37(5):720-4.

Flufenamic acid is a tool for investigating TRPC6-mediated calcium signalling in - Flufenamic acid is a tool for investigating TRPC6-mediated calcium signalling in

Foster RR, Zadeh MA, Welsh GI, Satchell SC, Ye Y, Mathieson PW, Bates DO, Saleem MA. Cell Calcium. 2009 Apr;45(4):384-90.

Diacylglycerol analogues activate second messenger-operated calcium channels - Diacylglycerol analogues activate second messenger-operated calcium channels

Tu P, Kunert-Keil C, Lucke S, Brinkmeier H, Bouron A. J Neurochem. 2009 Jan;108(1):126-38.

Nonsteroidal anti-inflammatory drug flufenamic acid is a potent activator of - Nonsteroidal anti-inflammatory drug flufenamic acid is a potent activator of

Chi Y, Li K, Yan Q, Koizumi S, Shi L, Takahashi S, Zhu Y, Matsue H, Takeda M, Kitamura M, Yao J. J Pharmacol Exp Ther. 2011 Oct;339(1):257-66.