Fluoxetine hydrochloride

• Supplier: Tocris Bioscience
• Catalog: 3257
• Prices: $89.00, $375.00
• Sizes: 10 mg, 50 mg
• Function Type: Inhibitor
• Cas Number: 56296-78-7
• Chemical Name: N-Methyl-3-[(4-trifluoromethyl)phenoxy]-3-phenylpropylaminehydrochloride
• Formula: C17H18F3NO.HCl
• Molecular Weight: 345.78
• Purity: >99 %
• Description: Selective serotonin reuptake inhibitor. Binds to the human 5-HT transporter with a K i of 0.9 nmol/l and is between 150- and 900- fold selective over 5-HT 1A , 5-HT 2A , H 1 , α 1 , α 2 -adrenergic, and muscarinic receptors. Antidepressant. Induces differentiation of neuronal precursors, enhancing neuronal characteristics.

Product References

Activation and desensitization of AMPA/kainate receptors by novel derivatives of - Activation and desensitization of AMPA/kainate receptors by novel derivatives of

Patneau DK, Mayer ML, Jane DE, Watkins JC. J Neurosci. 1992 Feb;12(2):595-606.

Willardiines differentiate agonist binding sites for kainate- versus - Willardiines differentiate agonist binding sites for kainate- versus

Wong LA, Mayer ML, Jane DE, Watkins JC. J Neurosci. 1994 Jun;14(6):3881-97.

Binding of the new radioligand (S)-[3H]AMPA to rat brain synaptic membranes: - Binding of the new radioligand (S)-[3H]AMPA to rat brain synaptic membranes:

Hawkins LM, Beaver KM, Jane DE, Taylor PM, Sunter DC, Roberts PJ. Neuropharmacology. 1995 Apr;34(4):405-10.

Synthesis of willardiine and 6-azawillardiine analogs: pharmacological - Synthesis of willardiine and 6-azawillardiine analogs: pharmacological

Jane DE, Hoo K, Kamboj R, Deverill M, Bleakman D, Mandelzys A. J Med Chem. 1997 Oct 24;40(22):3645-50.