(+)-Fluprostenol

• Supplier: Tocris Bioscience
• Catalog: 2867
• Prices: $75.00
• Sizes: 1 mg
• Function Type: Agonist
• Cas Number: 54276-17-4
• Chemical Name: (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]cyclopentyl]-5-heptenoicacid
• Formula: C23H29F3O6
• Molecular Weight: 458.47
• Purity: >95 %
• Description: Prostaglandin F 2 α (FP) receptor agonist (K i = 49.9 nM; EC 50 = 2.4 nM). Stimulates intracellular calcium mobilization in cloned human ocular FP receptors, rat A7r5 cells and mouse 3T3 cells (EC 50 values are 17.5, 19.1 and 37.3 nM respectively). Analog of prostaglandin F 2 α . Isopropyl ester travaprost (Cat. No. 4218) also available.

Product References

Real-time intracellular Ca2+ mobilization by travoprost acid, bimatoprost, - Real-time intracellular Ca2+ mobilization by travoprost acid, bimatoprost,

Kelly CR, Williams GW, Sharif NA. J Pharmacol Exp Ther. 2003 Jan;304(1):238-45.

Human trabecular meshwork cell responses induced by bimatoprost, travoprost, - Human trabecular meshwork cell responses induced by bimatoprost, travoprost,

Sharif NA, Kelly CR, Crider JY. Invest Ophthalmol Vis Sci. 2003 Feb;44(2):715-21.