Flurbiprofen

Name Flurbiprofen
Supplier Tocris Bioscience
Catalog 4542
Prices $75.00
Sizes 100 mg
Function Type Inhibitor
Cas Number 5104-49-4
Chemical Name 2-Fluoro-α-methyl-[1,1'-biphenyl]-4-aceticacid
Formula C15H13FO2
Molecular Weight 244.26
Purity >99 %
Description Potent inhibitor of cyclooxygenase (IC 50 values are 0.1 and 0.4 μ M for inhibition of human COX-1 and COX-2 respectively). Analgesic, anti-inflammatory and antipyretic in vivo . Inhibits tumor cell growth in vitro and in vivo . Regulates prostate stem cell antigen through activation of Akt kinase. Also inhibits fibroblast proliferation in vitro .
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Product References

The pharmacology of 2-(2-fluoro-4-biphenylyl)propionic acid (flurbiprofen). A - The pharmacology of 2-(2-fluoro-4-biphenylyl)propionic acid (flurbiprofen). A

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Expression and selective inhibition of the constitutive and inducible forms of - Expression and selective inhibition of the constitutive and inducible forms of

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Gene expression profiling in R-flurbiprofen-treated prostate cancer: - Gene expression profiling in R-flurbiprofen-treated prostate cancer:

Zemskova M, Wechter W, Bashkirova S, Chen CS, Reiter R, Lilly MB. Biochem Pharmacol. 2006 Nov 15;72(10):1257-67. Epub 2006 Sep 1.