Flurizan

• Supplier: Tocris Bioscience
• Catalog: 1769
• Prices: $95.00
• Sizes: 50 mg
• Cas Number: 51543-40-9
• Chemical Name: (R)-2-Fluoro-α-methyl[1,1'-biphenyl]-4-aceticacid
• Formula: C15H13FO2
• Molecular Weight: 244.26
• Purity: >99 %
• Description: Nonsteroidal anti-inflammatory drug (NSAID) that inhibits γ -secretase activity. Selectively lowers A β 42 levels in human neuroglioma cells; displays no effect on A β 40 levels at a concentration of 100 μ M.

Product References

NSAIDs and enantiomers of flurbiprofen target gamma-secretase and lower Abeta 42 - NSAIDs and enantiomers of flurbiprofen target gamma-secretase and lower Abeta 42

Eriksen JL, Sagi SA, Smith TE, Weggen S, Das P, McLendon DC, Ozols VV, Jessing KW, Zavitz KH, Koo EH, Golde TE. J Clin Invest. 2003 Aug;112(3):440-9.

Chronic administration of R-flurbiprofen attenuates learning impairments in - Chronic administration of R-flurbiprofen attenuates learning impairments in

Kukar T, Prescott S, Eriksen JL, Holloway V, Murphy MP, Koo EH, Golde TE, Nicolle MM. BMC Neurosci. 2007 Jul 24;8:54.