Flutax 1

Name Flutax 1
Supplier Tocris Bioscience
Catalog 4094
Prices $209.00
Sizes 1 mg
Cas Number 191930-58-2
Chemical Name (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-Bis(acetyloxy)-9-[(2R,3S)-3-(benzoylamino)-2-hydroxy-1-oxo-3-phenylpropoxy]-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11-hydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-4-ylesterN-[(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)carbonyl]-L-alanine
Formula C71H66N2O21
Molecular Weight 1283.3
Purity >98 %
Description A fluorescent taxol derivative that binds to the taxol microtubule binding site with high affinity (K a ~ 10 7 M -1 ). Useful for direct imaging of the microtubule cytoskeleton. Excitation maximum ~ 495 nm; emission maximum ~ 520 nm.
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Product References

Molecular recognition of taxol by microtubules. Kinetics and thermodynamics of - Molecular recognition of taxol by microtubules. Kinetics and thermodynamics of

Diaz JF, Strobe R, Engelborghs Y, Souto AA, Andreu JM. J Biol Chem. 2000 Aug 25;275(34):26265-76.

Fast kinetics of Taxol binding to microtubules. Effects of solution variables and - Fast kinetics of Taxol binding to microtubules. Effects of solution variables and

Diaz JF, Barasoain I, Andreu JM. J Biol Chem. 2003 Mar 7;278(10):8407-19. Epub 2002 Dec 20.