Fluvastatin sodium

• Supplier: Tocris Bioscience
• Catalog: 2007
• Prices: $115.00
• Sizes: 50 mg
• Function Type: Inhibitor
• Cas Number: 93957-55-2
• Chemical Name: (±)-(3R*,5S*,6E)-7-[3-(4-Fluorophenyl)-1-(1-methyethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoicacidsodiumsalt
• Formula: C24H25FNNaO4
• Molecular Weight: 433.45
• Purity: >98 %
• Description: Orally active, potent and competitive HMG-CoA reductase inhibitor (IC 50 = 40 -100 nM at human liver microsomes). Inhibits vascular smooth muscle proliferation in vitro (IC 50 = 70 nM) and exhibits antihypercholesterolemic and antioxidant activity in vivo .

Product References

HMG-CoA reductase activity in human liver microsomes: comparative inhibition by - HMG-CoA reductase activity in human liver microsomes: comparative inhibition by

Dansette PM, Jaoen M, Pons C. Exp Toxicol Pathol. 2000 May;52(2):145-8.

Antioxidative effect of fluvastatin, an inhibitor of 3-hydroxy-3-methylglutaryl - Antioxidative effect of fluvastatin, an inhibitor of 3-hydroxy-3-methylglutaryl

Yamamoto A, Ichihara K, Hoshi K. J Pharm Pharmacol. 2001 Feb;53(2):227-32.

Comparison of the efficacies of five different statins on inhibition of human - Comparison of the efficacies of five different statins on inhibition of human

Turner NA, Midgley L, O'Regan DJ, Porter KE. J Cardiovasc Pharmacol. 2007 Oct;50(4):458-61.