Formoterol hemifumarate

• Supplier: Tocris Bioscience
• Catalog: 1033
• Prices: $139.00, $585.00
• Sizes: 10 mg, 50 mg
• Function Type: Agonist
• Cas Number: 43229-80-7
• Chemical Name: (±)-(R,R)-N-[2-Hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]formamidehemifumarate
• Formula: C19H24N2O4.½C4H4O4
• Molecular Weight: 402.45
• Purity: >99 %
• Description: Potent, selective and long-acting β 2 -adrenoceptor agonist. Displays 330-fold selectivity for β 2 over β 1 receptors (pK d values are 8.12 and 5.58 respectively). Potently relaxes guinea pig trachea (pD 2 = 9.29), and is longer-acting and 100-fold more potent than salbutamol.

Product References

Effects of N-aralkyl substitution of beta-agonists on alpha- and - Effects of N-aralkyl substitution of beta-agonists on alpha- and

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Formoterol: pharmacology, molecular basis of agonism, and mechanism of long - Formoterol: pharmacology, molecular basis of agonism, and mechanism of long

Anderson GP. Life Sci. 1993;52(26):2145-60.

Relaxant effects and durations of action of formoterol and salmeterol on the - Relaxant effects and durations of action of formoterol and salmeterol on the

Naline E, Zhang Y, Qian Y, Mairon N, Anderson GP, Grandordy B, Advenier C. Eur Respir J. 1994 May;7(5):914-20.