FPL 64176

Name FPL 64176
Supplier Tocris Bioscience
Catalog 2276
Prices $129.00, $535.00
Sizes 10 mg, 50 mg
Function Type Activator
Cas Number 120934-96-5
Chemical Name 2,5-Dimethyl-4-[2-(phenylmethyl)benzoyl]-1H-pyrrole-3-carboxylicacidmethylester
Formula C22H21NO3
Molecular Weight 347.41
Purity >99 %
Description Potent activator of L-type Ca 2+ channels (EC 50 = 16 nM). 40-fold more potent than Bay K 8644 (Cat. No. 1544) as a positive inotrope in guinea pig atria.
Supplier Page Shop

Product References

Pharmacological, radioligand binding, and electrophysiological characteristics of - Pharmacological, radioligand binding, and electrophysiological characteristics of

Zheng W, Rampe D, Triggle DJ. Mol Pharmacol. 1991 Nov;40(5):734-41.

Discovery and synthesis of methyl 2,5-dimethyl-4-[2- - Discovery and synthesis of methyl 2,5-dimethyl-4-[2-

Baxter AJ, Dixon J, Ince F, Manners CN, Teague SJ. J Med Chem. 1993 Sep 17;36(19):2739-44.

Comparison of the in vitro and in vivo cardiovascular effects of two structurally - Comparison of the in vitro and in vivo cardiovascular effects of two structurally

Rampe D, Anderson B, Rapien-Pryor V, Li T, Dage RC. J Pharmacol Exp Ther. 1993 Jun;265(3):1125-30.