FR 236924

• Supplier: Tocris Bioscience
• Catalog: 3706
• Prices: $165.00
• Sizes: 10 mg
• Function Type: Activator
• Cas Number: 28399-31-7
• Chemical Name: 2-[(2-Pentylcyclopropyl)methyl]cyclopropaneoctanoicacid
• Formula: C20H36O2
• Molecular Weight: 308.5
• Purity: >99 %
• Description: Selective PKC ε activator that displays > 7-fold selectivity over other PKC isozymes. Stimulates glutamate release via presynaptic α 7 nicotinic receptors on glutamatergic terminals in vitro and enhances cognition in vivo . Brain penetrant.

Product References

The linoleic acid derivative FR236924 facilitates hippocampal synaptic - The linoleic acid derivative FR236924 facilitates hippocampal synaptic

Yamamoto S, Kanno T, Nagata T, Yaguchi T, Tanaka A, Nishizaki T. Neuroscience. 2005;130(1):207-13.

The linoleic acid derivative DCP-LA selectively activates PKC-epsilon, possibly - The linoleic acid derivative DCP-LA selectively activates PKC-epsilon, possibly

Kanno T, Yamamoto H, Yaguchi T, Hi R, Mukasa T, Fujikawa H, Nagata T, Yamamoto S, Tanaka A, Nishizaki T. J Lipid Res. 2006 Jun;47(6):1146-56. Epub 2006 Mar 6.