FTY 720

• Supplier: Tocris Bioscience
• Catalog: 5000
• Prices: $85.00, $359.00
• Sizes: 10 mg, 50 mg
• Function Type: Agonist
• Cas Number: 162359-56-0
• Chemical Name: 2-Amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diolhydrochloride
• Formula: C19H33NO2.HCl
• Molecular Weight: 343.93
• Purity: >99 %
• Description: S1P receptor agonist; undergoes phosphorylation by sphingosine kinase 2, which then binds S1P 1 , 3 , 4 and 5 receptors (EC 50 values are 0.3 - 0.6 nM for S1P 1 , 4 and 5 and ~3 nM for S1P 3 ). Immunosuppresent; sequesters lymphocytes in lymph nodes, reducing autoimmune response. Suppresses the development of EAE (an in vivo model of MS). Orally bioavailable and blood-brain barrier permeable.

Product References

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