Furosemide

• Supplier: Tocris Bioscience
• Catalog: 5202
• Prices: $49.00
• Sizes: 50 mg
• Cas Number: 54-31-9
• Chemical Name: 5-(Aminosulfonyl)-4-chloro-2-([2-furanylmethyl]amino)benzoicacid
• Formula: C12H11ClN2O5S
• Molecular Weight: 330.74
• Purity: >99 %
• Description: Loop diuretic that inhibits the Na + /2Cl - /K + (NKCC) symporter. Also acts as a non-competitive antagonist at GABA A receptors with ~ 100-fold greater selectivity for α 6-containing receptors than α 1-containing receptors.

Product References

Anticonvulsant actions of furosemide in vitro. - Anticonvulsant actions of furosemide in vitro.

Gutschmidt KU, Stenkamp K, Buchheim K, Heinemann U, Meierkord H. Neuroscience. 1999;91(4):1471-81.

Residues in transmembrane domains I and II determine gamma-aminobutyric acid type - Residues in transmembrane domains I and II determine gamma-aminobutyric acid type

Thompson SA, Arden SA, Marshall G, Wingrove PB, Whiting PJ, Wafford KA. Mol Pharmacol. 1999 Jun;55(6):993-9.