Galloflavin

• Supplier: Tocris Bioscience
• Catalog: 3090
• Prices: $155.00
• Sizes: 10 mg
• Function Type: Inhibitor
• Cas Number: 1780260-20-9
• Chemical Name: 3,8,9,10-Tetrahydroxypyrano[3,2-c][2]benzopyran-2,6-dionepotassiumsalt
• Formula: C12H5O8K
• Molecular Weight: 316.26
• Purity: >95 %
• Description: Inhibitor of human lactate dehydrogenase (LDH) (K i values are 5.46 and 15.1 μ M for LDH-A and LDH-B, respectively, in competition with pyruvate). Inhibits lactate production and decreases ATP synthesis in PLD/PRF/5 cells; thought to decrease cell viability via impairment of aerobic glycolysis.

Product References

Galloflavin, a new lactate dehydrogenase inhibitor, induces the death of human - Galloflavin, a new lactate dehydrogenase inhibitor, induces the death of human

Farabegoli F, Vettraino M, Manerba M, Fiume L, Roberti M, Di Stefano G. Eur J Pharm Sci. 2012 Nov 20;47(4):729-38.

Galloflavin (CAS 568-80-9): a novel inhibitor of lactate dehydrogenase. - Galloflavin (CAS 568-80-9): a novel inhibitor of lactate dehydrogenase.

Manerba M, Vettraino M, Fiume L, Di Stefano G, Sartini A, Giacomini E, Buonfiglio R, Roberti M, Recanatini M. ChemMedChem. 2012 Feb 6;7(2):311-7.

Galloflavin prevents the binding of lactate dehydrogenase A to single stranded - Galloflavin prevents the binding of lactate dehydrogenase A to single stranded

Fiume L, Vettraino M, Carnicelli D, Arfilli V, Di Stefano G, Brigotti M. Biochem Biophys Res Commun. 2013 Jan 11;430(2):466-9. doi: