GBR 12783 dihydrochloride

• Supplier: Tocris Bioscience
• Catalog: 2348
• Prices: $119.00, $505.00
• Sizes: 10 mg, 50 mg
• Function Type: Inhibitor
• Cas Number: 67469-75-4
• Chemical Name: 1-(2-Diphenylmethoxyethyl)-4-(3-phenyl-2-propenyl)-piperazinedihydrochloride
• Formula: C28H32N2O.2HCl
• Molecular Weight: 485.5
• Purity: >99 %
• Description: A very potent and selective inhibitor of dopamine uptake (IC 50 for inhibition of [ 3 H]-dopamine uptake in rat striatal synaptosomes is 1.8 nM).

Product References

GBR 12783, a potent and selective inhibitor of dopamine uptake: biochemical - GBR 12783, a potent and selective inhibitor of dopamine uptake: biochemical

Bonnet JJ, Costentin J. Eur J Pharmacol. 1986 Feb 18;121(2):199-209.

Cloning, pharmacological characterization, and chromosome assignment of the human - Cloning, pharmacological characterization, and chromosome assignment of the human

Giros B, el Mestikawy S, Godinot N, Zheng K, Han H, Yang-Feng T, Caron MG. Mol Pharmacol. 1992 Sep;42(3):383-90.

In vivo labelling of the neuronal dopamine uptake complex in the mouse striatum - In vivo labelling of the neuronal dopamine uptake complex in the mouse striatum

Vaugeois JM, Bonnet JJ, Costentin J. Eur J Pharmacol. 1992 Jan 7;210(1):77-84.

Evidence for the sequential formation of two complexes between an uptake - Evidence for the sequential formation of two complexes between an uptake

Do-Rego JC, Hue H, Costentin J, Bonnet JJ. J Neurochem. 1999 Jan;72(1):396-404.