[Des-octanoyl]-Ghrelin (human)

• Supplier: Tocris Bioscience
• Catalog: 1346
• Prices: $225.00
• Sizes: 1 mg
• Cas Number: 313951-59-6
• Formula: C141H235N47O41
• Molecular Weight: 3244.51
• Description: Non-acylated, major circulating isoform of ghrelin that does not bind to the ghrelin receptor (GHS-R1a), nor induce growth hormone release. However, exerts negative inotropic effects in papillary muscle and displays cardioprotective activity. Inhibits cell proliferation in breast and prostate cancer cell lines. Promotes adipogenesis in vivo .

Product References

Ghrelin and des-acyl ghrelin inhibit cell death in cardiomyocytes and endothelial - Ghrelin and des-acyl ghrelin inhibit cell death in cardiomyocytes and endothelial

Baldanzi G, Filigheddu N, Cutrupi S, Catapano F, Bonissoni S, Fubini A, Malan D, Baj G, Granata R, Broglio F, Papotti M, Surico N, Bussolino F, Isgaard J, Deghenghi R, Sinigaglia F, Prat M, Muccioli G, Ghigo E, Graziani A. J Cell Biol. 2002 Dec 23;159(6):1029-37. Epub 2002 Dec 16.

Cardiac effects of ghrelin and its endogenous derivatives des-octanoyl ghrelin - Cardiac effects of ghrelin and its endogenous derivatives des-octanoyl ghrelin

Bedendi I, Alloatti G, Marcantoni A, Malan D, Catapano F, Ghe C, Deghenghi R, Ghigo E, Muccioli G. Eur J Pharmacol. 2003 Aug 22;476(1-2):87-95.

Expression of ghrelin and biological activity of specific receptors for ghrelin - Expression of ghrelin and biological activity of specific receptors for ghrelin

Cassoni P, Ghe C, Marrocco T, Tarabra E, Allia E, Catapano F, Deghenghi R, Ghigo E, Papotti M, Muccioli G. Eur J Endocrinol. 2004 Feb;150(2):173-84.

Ghrelin and des-octanoyl ghrelin promote adipogenesis directly in vivo by a - Ghrelin and des-octanoyl ghrelin promote adipogenesis directly in vivo by a

Thompson NM, Gill DA, Davies R, Loveridge N, Houston PA, Robinson IC, Wells T. Endocrinology. 2004 Jan;145(1):234-42. Epub 2003 Oct 9.