Ginkgolide B

• Supplier: Tocris Bioscience
• Catalog: 3995
• Prices: $89.00, $375.00
• Sizes: 10 mg, 50 mg
• Function Type: Antagonist
• Cas Number: 15291-77-7
• Chemical Name: (1R,3S,3aS,4R,6aR,7aR,7bR,8S,10aS,11R,11aR)-3-(1,1-Dimethylethyl)hexahydro-4,7b,11-trihydroxy-8-methyl-9H-1,7a-(epoxymethano)-1H,6aH-cyclopenta[c]furo[2,3-b]furo[3',2':3,4]cyclopenta[1,2-d]furan-5,9,12(4H)-trione
• Formula: C20H24O10
• Molecular Weight: 424.4
• Description: Platelet-activating factor (PAF) receptor antagonist (K i = 1.3 μ M). Inhibits neutrophil degranulation and superoxide production in vitro and inhibits bronchoconstriction and is neuroprotective following oral administration in vivo .

Product References

Interference of BN 52021 (ginkgolide B) with the bronchopulmonary effects of - Interference of BN 52021 (ginkgolide B) with the bronchopulmonary effects of

Desquand S, Touvay C, Randon J, Lagente V, Vilain B, Maridonneau-Parini I, Etienne A, Lefort J, Braquet P, Vargaftig BB. Eur J Pharmacol. 1986 Aug 7;127(1-2):83-95.

Inhibition by BN 52021 (ginkgolide B) of the binding of [3H]-platelet-activating - Inhibition by BN 52021 (ginkgolide B) of the binding of [3H]-platelet-activating

Foldes-Filep E, Braquet P, Filep J. Biochem Biophys Res Commun. 1987 Nov 13;148(3):1412-7.

The CNS effects of Ginkgo biloba extracts and ginkgolide B. - The CNS effects of Ginkgo biloba extracts and ginkgolide B.

Maclennan KM, Darlington CL, Smith PF. Prog Neurobiol. 2002 Jun;67(3):235-57.