cGMP Dependent Kinase Inhibitor Peptide

Name cGMP Dependent Kinase Inhibitor Peptide
Supplier Tocris Bioscience
Catalog 2983
Prices $105.00
Sizes 1 mg
Function Type Inhibitor
Cas Number 82801-73-8
Formula C38H74N18O10
Molecular Weight 943.12
Description Competitive inhibitor of cGMP-dependent protein kinase (PKG); analog of a substrate peptide corresponding to a phosphorylation site of histone H2B. Competes with synthetic substrates (K i = 86 mM) but does not inhibit phosphorylation of intact histones by PKG. Inhibits phosphorylation of intact histones by PKA.
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Product References

Differential responses of cyclic GMP-dependent and cyclic AMP-dependent protein - Differential responses of cyclic GMP-dependent and cyclic AMP-dependent protein

Glass DB. Biochem J. 1983 Jul 1;213(1):159-64.

Differential and common recognition of the catalytic sites of the cGMP-dependent - Differential and common recognition of the catalytic sites of the cGMP-dependent

Glass DB, Cheng HC, Kemp BE, Walsh DA. J Biol Chem. 1986 Sep 15;261(26):12166-71.

Synthetic peptide analogues differentially alter the binding affinities of cyclic - Synthetic peptide analogues differentially alter the binding affinities of cyclic

Bhatnagar D, Glass DB, Roskoski R Jr, Lessor RA, Leonard NJ. Biochemistry. 1988 Mar 22;27(6):1988-94.