| Name | Go 6983 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 2253 |
| Prices | $105.00, $225.00 |
| Sizes | 1 mg, 10 mg |
| Function Type | Inhibitor |
| Cas Number | 133053-19-7 |
| Chemical Name | 3-[1-[3-(Dimethylamino)propyl]-5-methoxy-1H-indol-3-yl]-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione |
| Formula | C26H26N4O3 |
| Molecular Weight | 442.51 |
| Purity | >98 % |
| Description | Broad spectrum protein kinase C (PKC) inhibitor (IC 50 values are 7, 7, 6, 10, 60 and 20000 nM for PKC α , PKC β , PKC γ , PKC δ , PKC ζ and PKC μ respectively). Displays cardioprotective properties; reduces polymorphonuclear leukocyte adherence and infiltration following myocardial ischemia/reperfusion injury. Optimizes naïve human pluripotent stem cell growth and viability following naïve cell derivation from primed ESCs and iPSCs using naïve human stem cell medium (NHSM). |
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