Golgicide A

Name Golgicide A
Supplier Tocris Bioscience
Catalog 2285
Prices $199.00, $825.00
Sizes 10 mg, 50 mg
Function Type Inhibitor
Cas Number 1139889-93-2
Chemical Name 6,8-Difluoro-4-pyridin-3-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline
Formula C17H14F2N2
Molecular Weight 284.3
Purity >98 %
Description Potent, specific and reversible inhibitor of Golgi BFA resistance factor 1 (GBF1), an ArfGEF, that decreases Arf1 activation in vivo . Arrests secretion of soluble and membrane-associated proteins at the endoplasmic reticulum-Golgi intermediate compartment. Causes disassembly and dispersal of the Golgi and trans -Golgi network.
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