GP 1a

• Supplier: Tocris Bioscience
• Catalog: 1964
• Prices: $225.00, $925.00
• Sizes: 10 mg, 50 mg
• Function Type: Agonist
• Cas Number: 511532-96-0
• Chemical Name: N-(Piperidin-1-yl)-1-(2,4-dichlorophenyl)-1,4-dihydro-6-methylindeno[1,2-c]pyrazole-3-carboxamide
• Formula: C23H22Cl2N4O
• Molecular Weight: 441.35
• Purity: >99 %
• Description: Highly selective CB 2 receptor agonist; K i values are 0.037 and 363 nM for CB 2 and CB 1 receptors respectively. Increases P-ERK1/2 expression in HL-60 cells in vitro .

Product References

Tricyclic pyrazoles. 4. Synthesis and biological evaluation of analogues of the - Tricyclic pyrazoles. 4. Synthesis and biological evaluation of analogues of the

Murineddu G, Lazzari P, Ruiu S, Sanna A, Loriga G, Manca I, Falzoi M, Dessi C, Curzu MM, Chelucci G, Pani L, Pinna GA. J Med Chem. 2006 Dec 14;49(25):7502-12.

The cannabinoid receptor 2 is critical for the host response to sepsis. - The cannabinoid receptor 2 is critical for the host response to sepsis.

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