GPi 688

• Supplier: Tocris Bioscience
• Catalog: 4478
• Prices: $235.00, $965.00
• Sizes: 10 mg, 50 mg
• Function Type: Inhibitor
• Cas Number: 918902-32-6
• Chemical Name: 2-Chloro-N-[1-[(2R)-2,3-dihydroxypropyl]-1,2,3,4-tetrahydro-2-oxo-3-quinolinyl]-6H-thieno[2,3-b]pyrrole-5-carboxamide
• Formula: C19H18ClN3O4S
• Molecular Weight: 419.88
• Purity: >99 %
• Description: Allosteric glycogen phosphorylase inhibitor; acts at the indole site of glycogen phosphorylase. Inhibits glucagon-mediated hyperglycemia in vivo in the rat.

Product References

Sensitivity of glycogen phosphorylase isoforms to indole site inhibitors is - Sensitivity of glycogen phosphorylase isoforms to indole site inhibitors is

Freeman S, Bartlett JB, Convey G, Hardern I, Teague JL, Loxham SJ, Allen JM, Poucher SM, Charles AD. Br J Pharmacol. 2006 Nov;149(6):775-85. Epub 2006 Oct 3.

An assessment of the in vivo efficacy of the glycogen phosphorylase inhibitor - An assessment of the in vivo efficacy of the glycogen phosphorylase inhibitor

Poucher SM, Freeman S, Loxham SJ, Convey G, Bartlett JB, De Schoolmeester J, Teague J, Walker M, Turnbull AV, Charles AD, Carey F, Berg S. Br J Pharmacol. 2007 Dec;152(8):1239-47. Epub 2007 Oct 15.