Name | GR 64349 |
---|---|
Supplier | Tocris Bioscience |
Catalog | 1054 |
Prices | $349.00 |
Sizes | 1 mg |
Function Type | Agonist |
Cas Number | 137593-52-3 |
Formula | C42H68N10O11S |
Molecular Weight | 921.12 |
Description | Potent and selective tachykinin NK 2 receptor agonist (EC 50 = 3.7 nM in rat colon). Displays > 1000- and > 300-fold selectivity over NK 1 and NK 3 receptors respectively. Active in vivo . |
Supplier Page | Shop |
Deal MJ, Hagan RM, Ireland SJ, Jordan CC, McElroy AB, Porter B, Ross BC, Stephens-Smith M, Ward P. J Med Chem. 1992 Oct 30;35(22):4195-204.
Chizh BA, Cumberbatch MJ, Birch PJ, Headley PM. Br J Pharmacol. 1995 Jul;115(6):1013-9.
Chang Y, Hoover DB, Hancock JC, Smith FM. J Pharmacol Exp Ther. 2000 Jul;294(1):147-54.