GR 89696 fumarate

• Supplier: Tocris Bioscience
• Catalog: 1670
• Prices: $159.00, $665.00
• Sizes: 10 mg, 50 mg
• Function Type: Agonist
• Cas Number: 126766-32-3
• Chemical Name: 4-[(3,4-Dichlorophenyl)acetyl]-3-(1-pyrrolidinylmethyl)-1-piperazinecarboxylicacidmethylesterfumarate
• Formula: C19H25Cl2N3O3.C4H4O4
• Molecular Weight: 530.4
• Purity: >99 %
• Description: Highly potent and selective κ -opioid agonist (IC 50 = 0.04 nM) that may be selective for the putative κ 2 receptor. Anti-nociceptive and neuroprotective in vivo .

Product References

Neuroprotective actions of GR89696, a highly potent and selective kappa-opioid - Neuroprotective actions of GR89696, a highly potent and selective kappa-opioid

Birch PJ, Rogers H, Hayes AG, Hayward NJ, Tyers MB, Scopes DI, Naylor A, Judd DB. Br J Pharmacol. 1991 Jul;103(3):1819-23.

A potent new class of kappa-receptor agonist: 4-substituted - A potent new class of kappa-receptor agonist: 4-substituted

Naylor A, Judd DB, Lloyd JE, Scopes DI, Hayes AG, Birch PJ. J Med Chem. 1993 Jul 23;36(15):2075-83.

GR89,696: a potent kappa-opioid agonist with subtype selectivity in rhesus - GR89,696: a potent kappa-opioid agonist with subtype selectivity in rhesus

Butelman ER, Ko MC, Traynor JR, Vivian JA, Kreek MJ, Woods JH. J Pharmacol Exp Ther. 2001 Sep;298(3):1049-59.