Grifolic acid

• Supplier: Tocris Bioscience
• Catalog: 4779
• Prices: $165.00
• Sizes: 1 mg
• Function Type: Agonist
• Cas Number: 80557-12-6
• Chemical Name: 2,4-Dihydroxy-6-methyl-3-[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrien-1-yl]-benzoicacid
• Formula: C23H32O4
• Molecular Weight: 372.5
• Purity: >98 %
• Description: Selective partial FFA4 (GPR120) agonist. Induces ERK and [Ca 2+ ] i responses in cells expressing GPR120, but not those expressing GPR40.

Product References

Novel selective ligands for free fatty acid receptors GPR120 and GPR40. - Novel selective ligands for free fatty acid receptors GPR120 and GPR40.

Hara T, Hirasawa A, Sun Q, Sadakane K, Itsubo C, Iga T, Adachi T, Koshimizu TA, Hashimoto T, Asakawa Y, Tsujimoto G. Naunyn Schmiedebergs Arch Pharmacol. 2009 Sep;380(3):247-55. doi:

Structure-activity relationships of GPR120 agonists based on a docking - Structure-activity relationships of GPR120 agonists based on a docking

Sun Q, Hirasawa A, Hara T, Kimura I, Adachi T, Awaji T, Ishiguro M, Suzuki T, Miyata N, Tsujimoto G. Mol Pharmacol. 2010 Nov;78(5):804-10.