| Name | GSK 319347A |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 5189 |
| Prices | $379.00 |
| Sizes | 10 mg |
| Function Type | Inhibitor |
| Cas Number | 862812-98-4 |
| Chemical Name | 5-(5,6-Dimethoxy-1H-benzimidazol-1-yl)-3-[[2-(methylsulfonyl)phenyl]methoxy]-2-thiophenecarbonitrile |
| Formula | C22H19N3O5S2 |
| Molecular Weight | 469.53 |
| Purity | >98 % |
| Description | Potent and selective IKK ε inhibitor (pIC 50 = 7.4). Exhibits >100-fold selectivity for IKK ε over IKK α IKK β , and a range of other kinases. |
| Supplier Page | Shop |
Palkar PS, Borland MG, Naruhn S, Ferry CH, Lee C, Sk UH, Sharma AK, Amin S, Murray IA, Anderson CR, Perdew GH, Gonzalez FJ, Muller R, Peters JM. Mol Pharmacol. 2010 Sep;78(3):419-30.
Shearer BG, Wiethe RW, Ashe A, Billin AN, Way JM, Stanley TB, Wagner CD, Xu RX, Leesnitzer LM, Merrihew RV, Shearer TW, Jeune MR, Ulrich JC, Willson TM. J Med Chem. 2010 Feb 25;53(4):1857-61.