GSK J5

• Supplier: Tocris Bioscience
• Catalog: 4594
• Prices: $199.00, $825.00
• Sizes: 10 mg, 50 mg
• Cas Number: 1394854-51-3
• Chemical Name: N-[2-(3-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-β-alanineethylester
• Formula: C24H27N5O2
• Molecular Weight: 417.5
• Purity: >98 %
• Description: Inactive isomer of GSK J4 (Cat. No. 4594); also cell permeable ester derivative of the inactive control, GSK J2 (Cat. No. 4688)

Product References

A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory - A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory

Kruidenier L, Chung CW, Cheng Z, Liddle J, Che K, Joberty G, Bantscheff M, Bountra C, Bridges A, Diallo H, Eberhard D, Hutchinson S, Jones E, Katso R, Leveridge M, Mander PK, Mosley J, Ramirez-Molina C, Rowland P, Schofield CJ, Sheppard RJ, Smith JE, Swales C, Tanner R, Thomas P, Tumber A, Drewes G, Oppermann U, Patel DJ, Lee K, Wilson DM. Nature. 2012 Aug 16;488(7411):404-8.