| Name | GTS 21 dihydrochloride |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 2086 |
| Prices | $189.00, $765.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Antagonist |
| Cas Number | 156223-05-1 |
| Chemical Name | 3-[(2,4-Dimethoxyphenyl)methylene]-3,4,5,6-tetrahydro-2,3'-bipyridinedihydrochloride |
| Formula | C19H20N2O2.2HCl |
| Molecular Weight | 381.3 |
| Purity | >98 % |
| Description | Partial agonist of α 7 nicotinic acetylcholine receptors (nAChRs); also a weak α 4 β 2 and 5-HT 3 antagonist at micromolar concentrations. Exhibits improved sensory inhibition in DBA/2 mice following both acute and chronic administration. Also shown to improve memory in several animal models; facilitates hippocampal long-term potentiation. |
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