Guvacine hydrochloride

• Supplier: Tocris Bioscience
• Catalog: 3570
• Prices: $175.00
• Sizes: 100 mg
• Function Type: Inhibitor
• Cas Number: 6027-91-4
• Chemical Name: 1,2,5,6-Tetrahydropyridine-3-carboxylicacidhydrochloride
• Formula: C6H9NO2.HCl
• Molecular Weight: 163.6
• Purity: >99 %
• Description: Specific GABA uptake inhibitor. IC 50 values are 14, 58, 119 and 1870 μ M for hGAT-1, rGAT-2, hGAT-3 and hBGT-1 respectively.

Product References

Structure-activity studies on the inhibition of GABA binding to rat brain - Structure-activity studies on the inhibition of GABA binding to rat brain

Krogsgaard-Larsen P, Johnston GA. J Neurochem. 1978 Jun;30(6):1377-82.

Tiagabine, SK&F 89976-A, CI-966, and NNC-711 are selective for the cloned GABA - Tiagabine, SK&F 89976-A, CI-966, and NNC-711 are selective for the cloned GABA

Borden LA, Murali Dhar TG, Smith KE, Weinshank RL, Branchek TA, Gluchowski C. Eur J Pharmacol. 1994 Oct 14;269(2):219-24.