GW 1929 hydrochloride

• Supplier: Tocris Bioscience
• Catalog: 2229
• Prices: $199.00, $825.00
• Sizes: 10 mg, 50 mg
• Function Type: Agonist
• Cas Number: 1217466-21-1
• Chemical Name: N-(2-Benzoylphenyl)-O-[2-(methyl-2-pyridinylamino)ethyl]-L-tyrosinehydrochloride
• Formula: C30H29N3O4.HCl
• Molecular Weight: 532.03
• Purity: >98 %
• Description: Highly selective orally active peroxisome proliferator-activated receptor (PPAR) γ agonist (pEC 50 values are 8.05, < 4 and < 4 for human PPAR γ , PPAR α and PPAR δ receptors respectively). Decreases glucose, fatty acid and triglyceride levels following oral administration in vivo .

Product References

A novel N-aryl tyrosine activator of peroxisome proliferator-activated - A novel N-aryl tyrosine activator of peroxisome proliferator-activated

Brown KK, Henke BR, Blanchard SG, Cobb JE, Mook R, Kaldor I, Kliewer SA, Lehmann JM, Lenhard JM, Harrington WW, Novak PJ, Faison W, Binz JG, Hashim MA, Oliver WO, Brown HR, Parks DJ, Plunket KD, Tong WQ, Menius JA, Adkison K, Noble SA, Willson TM. Diabetes. 1999 Jul;48(7):1415-24.

Potentiation of glucose uptake in 3T3-L1 adipocytes by PPAR gamma agonists is - Potentiation of glucose uptake in 3T3-L1 adipocytes by PPAR gamma agonists is

Nugent C, Prins JB, Whitehead JP, Savage D, Wentworth JM, Chatterjee VK, O'Rahilly S. Mol Endocrinol. 2001 Oct;15(10):1729-38.

Adipose tissue resistin expression is severely suppressed in obesity and - Adipose tissue resistin expression is severely suppressed in obesity and

Way JM, Gorgun CZ, Tong Q, Uysal KT, Brown KK, Harrington WW, Oliver WR Jr, Willson TM, Kliewer SA, Hotamisligil GS. J Biol Chem. 2001 Jul 13;276(28):25651-3. Epub 2001 May 23.