GW 438014A

• Supplier: Tocris Bioscience
• Catalog: 2473
• Prices: $155.00, $645.00
• Sizes: 10 mg, 50 mg
• Function Type: Antagonist
• Cas Number: 469861-49-2
• Chemical Name: N-[1-(2-Phenylethyl)-1H-benzimidazol-2-yl]benzamidemethanesulfonate
• Formula: C22H19N3O.CH3SO3H
• Molecular Weight: 437.51
• Purity: >99 %
• Description: Neuropeptide (NPY) Y 5 receptor antagonist (IC 50 = 210 nM). Reduces NPY-induced food intake in rodents and decreases weight gain in obese rats.

Product References

Food intake inhibition and reduction in body weight gain in lean and obese - Food intake inhibition and reduction in body weight gain in lean and obese

Daniels AJ, Grizzle MK, Wiard RP, Matthews JE, Heyer D. Regul Pept. 2002 Jun 15;106(1-3):47-54.

Neuropeptide Y Y5 receptors inhibit kindling acquisition in rats. - Neuropeptide Y Y5 receptors inhibit kindling acquisition in rats.

Benmaamar R, Richichi C, Gobbi M, Daniels AJ, Beck-Sickinger AG, Vezzani A. Regul Pept. 2005 Feb 15;125(1-3):79-83.