| Name | GW 501516 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 2238 |
| Prices | $179.00, $745.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Agonist |
| Cas Number | 317318-70-0 |
| Chemical Name | 2-[2-Methyl-4-[[[4-methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl]methyl]thio]phenoxy]aceticacid |
| Formula | C21H18F3NO3S2 |
| Molecular Weight | 453.5 |
| Purity | >98 % |
| Description | Potent and selective PPAR δ agonist (EC 50 = 1.2 nM). Displays <1000-fold selectivity over other PPAR subtypes. Increases ABC A1 transporter expression and induces apolipoprotein A1-mediated cholesterol efflux in vitro . Also increase serum HDL cholesterol and lowers small, dense LDL levels in obesity in vivo models. |
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