| Name | GYKI 47261 dihydrochloride |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 1508 |
| Prices | $199.00, $825.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Antagonist |
| Cas Number | 1217049-32-5 |
| Chemical Name | 4-(8-Chloro-2-methyl-11H-imidazo[1,2-c][2,3]benzodiazepin-6-benzeneaminedihydrochloride |
| Formula | C18H15ClN4.2HCl |
| Molecular Weight | 395.71 |
| Purity | >99 % |
| Description | Non-competitive AMPA receptor antagonist (IC 50 = 2.5 μ M). Displays broad spectrum anticonvulsive activity and neuroprotective effects in vivo . |
| Supplier Page | Shop |
Abraham G, Solyom S, Csuzdi E, Berzsenyi P, Ling I, Tarnawa I, Hamori T, Pallagi I, Horvath K, Andrasi F, Kapus G, Harsing LG Jr, Kiraly I, Patthy M, Horvath G. Bioorg Med Chem. 2000 Aug;8(8):2127-43.
Bibbiani F, Oh JD, Kielaite A, Collins MA, Smith C, Chase TN. Exp Neurol. 2005 Dec;196(2):422-9. Epub 2005 Oct 3.