Glycyl-H 1152 dihydrochloride

Name Glycyl-H 1152 dihydrochloride
Supplier Tocris Bioscience
Catalog 2414
Prices $245.00
Sizes 1 mg
Function Type Inhibitor
Cas Number 913844-45-8
Chemical Name (S)-(+)-4-Glycyl-2-methyl-1-[(4-methyl-5-isoquinolinyl)sulfonyl]-hexahydro-1H-1,4-diazepinedihydrochloride
Formula C18H24N4O3S.2HCl
Molecular Weight 449.4
Purity >99 %
Description Glycyl analog of the Rho-kinase inhibitor H 1152 dihydrochloride (Cat. No. 2414) that displays improved ROCKII selectivity. IC 50 values are 0.0118, 2.35, 2.57, 3.26, > 10 and >10 μ M for ROCKII, Aurora A, CAMKII, PKG, PKA and PKC respectively.
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